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Rocky Mountain Axolotls
  • Home
  • Axolotl Care
  • SHOP
  • Terms and Conditions
  • SERVICES
  • Recommended Products
  • Axolotl Morphs
  • Downloadable FIles
  • Gallery
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Illness information and prevention

Axolotl first aid basics

 We are providing you basic information about different medications that are safe for axolotls and natural methods for treatment of mild illness.  However we do highly recommend that any time there is illness with your axolotl you seek an exotic veterinarian for professional diagnosis.  

Below are some items that are good to keep on hand in your axolotl first aid kit in case your axolotl gets sick or has fungus.

It is also good practice to locate an exotic vet near you who has experience treating axolotls and keep their information available if needed, Even if you do not need one at the time, you will thank us later when you need them so you do not have to stress about finding one later on. 

Note: these are just a few basic items, there are others that will treat less common illnesses you may need.  A fellow breeder has axolotl First Aid kits you can purchase with pretty much everything you may need that is available over the counter:  https://themottledlotl.com/products/pharmacy/

  • Indian almond leaves - these release tannins that help fight against bacteria, fungi and other similar organisms naturally.  You can use these as a preventative or as a  remedy for mild illnesses and injuries. 
  • Aquarium salt - Use this to make salt baths to treat mild illnesses and fungus.  Simply dissolve 1 teaspoon per 1 liter of water,  add Seachem Prime to remove any chlorine.  Soak your axolotl in the bath 1-2 times per day (depending on severity of illness or fungus) for 10 minutes.  Repeat as necessary.
  • Holtfreter's Salt Solution - One solution you can make and add to your water is Holtfreter's solution.  This solution helps keep down fungus and helps your axolotls immune system.  While Axolotls are a freshwater amphibian, adding these salts does not change the water from fresh to saltwater, since the amount of salt is small in comparison.  
    • Here is the Recipe:
      • Mix the following into 5 gallons of dechlorinated water: 
      • Mix 3 tablespoons sea salt or aquarium salt (NEVER use iodized salt!)
      • 1 teaspoon Epsom salt (containing no scents or dyes)
      • ⅛ teaspoon NuSalt (a salt replacer found near Morton Salt, it is potassium chloride)
  • API General Cure - treats a variety of parasites.
  • Methylene Blue - used to treat fungal infections  *make sure not to use too much, you want the water to just be lightly tinted blue, using too much is harmful to the animal. 
  • Nitrofurazone - used with methylene blue to treat fungal and bacterial diseases.
  • Seachem Kanaplex - treats some fungal and bacterial diseases.
  • Seachen Metroplex - treats  several protozoan and anaerobic bacterial diseases.
  • Seachem Focus - Used to bind other medication to food to treat internal bacterial infections. 
  • Prazipro - for parasite prevention

illness prevention

The most important things you can do to prevent illness is to cycle your tank before adding your axolotls, do weekly water changes, check you parameters weekly, clean up any uneaten food etc. 


Fungus is the most common issue, it appears like a white cotton like substance that is typically on the gills of the axolotl.  Salt baths will clear this up if caught early enough, but for fungus prevention you can add aquarium salt to your tank regularly.  Be sure to fully dissolve it first before adding it, you can safely add 1 tablespoon per 5 gallons of water.  This does not stop fungus and illness but it helps, and it adds good minerals to the water to make your axolotl happy.


Frequently check on your axolotl, make sure they are not showing signs of illness.  Some things to look for are;  abnormal changes to the skin, loss of weight, shrinking of the gills or gill filaments.  The first think to do when you suspect your axolotl may be sick is to check your water parameters to be sure they are within the ideal ranges.  Depending on severity of illness you will want to remove your axolotl from their tank and place them in a tub with 100% daily water changes until they are no longer ill.  This helps keep them in clean water and so you can better monitor them. 



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